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Semaglutide is something called a GLP-1 (or glucagon-like peptide-1) agonist
Daly C, Ghosh P, Jenkin G, Oehme D, Goldschlager T
Discussion Our studies demonstrate that intra-colonic administration of propionate stimulates the concurrent release of both GLP-1 and PYY in rodents, and demonstrate in vitro , and for the first time in vivo , that FFA2 deficiency impairs SCFA-induced gut hormone secretion
Given the prevalence of these chronic conditions, scientists are working to develop more effective treatments